Clarify a relationship between functions and structures of proteins on the basis of theoretical chemistry
Overview
Proteins consist of only 20 types of amino acids, while they show large variety in their functions, e.g., redox activity, transporter, sensor, and antibodies. Protein functions can be fully explained by the molecular structure even if the functions are seemingly complicated. To clarify a relationship between functions and structures of proteins, we analyze protein structures at an atomic level and calculate physical or chemical constants on the basis of theoretical chemistry. “Just computing molecules” is not in our interest. Our mission is to uncover new but simple principles essential to the protein science. For example, we are trying to clarify the reaction mechanisms of natural photosynthetic proteins, e.g., oxygen evolution, electron transfer, and proton transfer reactions. We also develop new tools for analysis of protein function.
- Instructor / Laboratory
- Hiroshi ISHIKITA
- ISHIKITA Laboratory
Hiroshi ISHIKITA / ISHIKITA Laboratory